Familial histiocytic reticulosis (familial haemophagocytic reticulosis).

Haemophagocytic reticulosis. A state of chimerism?

Haemophagocytic reticulosis is characterized by pancytopenia and an increased mass of reticuloendothelial cells in various organs containing engulfed blood cells (see Buist, Jones, and Cavens, 1971; Oehmichen, Narita, and Roloff, 1972; Nezelof and Eliachar, 1973). The pathogenesis is obscure. Autoimmunity, primary histiocytic proliferation, and a graft versus host reaction have been suggested. ...

Familial haemophagocytic reticulosis.

Familial erythrophagocytic reticulosis. Complete response to combination chemotherapy.

Two infants with familial erythrophagocytic reticulosis attained a durable complete remission after combination chemotherapy including intrathecal methotrexate. Though both later died, neither child had definitive evidence of tumour at necropsy.

Haemophagocytic lymphohistiocytosis: from diagnostic challenges to predictive possibilities.

In 1832 Thomas Hodgkin described ‘some morbid appearances of the absorbent glands and spleen’ in seven individuals with enlargements of lymph nodes and spleen without inflammation or other significant pathological findings. His initial description resolved into a multiplicity of pathological entities over the years. Indeed, among this wide group of disorders, the leucose, syphilitic and tubercu...

Histiocytic medullary reticulosis occurring with small cell lung carcinoma.

Haematophagocytic activity is a salient feature of malignant histiocytic medullary reticulosis. This potency has also been observed as an aberrant property of non-histiocytic malignant cells or as a benign histiocytic process in response to infections or malignancies. We report the case of a patient who presented simultaneously with a limited stage small cell lung carcinoma and a fatal reactive...